NOTCH2 and diffuse large B-cell lymphoma: The western blotting results showed that in mt Notch2 DLBCL cells (including OCI-ly3 and Pfeiffer), the phosphorylation levels of P65 and IκBα were up-regulated significantly compared with those in wt Notch2 cells and pLVX cells, and in wt Notch2 DLBCL cells they were higher than pLVX cells (Fig. 6A).