Recently, Hao and co-workers [68] showed that overexpression of CD147, CD44v3-10, MDR1 and MCT4 was associated with PCa progression and also that expression of both CD147 and CD44v3-10 correlates with drug resistance during PCa metastisation and could be a useful potential therapeutic target in advanced disease. The gene discussed is ABCB1; the disease is posterior cortical atrophy.