MAPK8 and neoplasm: In a panel of tumor cell lines of different tissues of origin, the sensitivity to DTP3-induced killing correlated with a very high degree of significance with the mRNA levels of GADD45B (Figure 5C; Figures S2G and S5U), which our data have shown is a pivotal NF-κB-regulated inhibitor of MKK7/JNK signaling and apoptosis in MM cells (Figures 2B–2E; Figures S2H–S2J and S2N–S2P).