Several research groups have attenuated the action of over-expressed Fzd7 in cancer cells using different methods such as an anti-FZD7 antibody, an extracellular peptide of FZD7 (soluble FZD7 peptide), small interfering peptides or a small molecule inhibitor [40], [47], [48], [49], [50], [51]. This evidence concerns the gene FZD7 and cancer.