In BEAS-2B cells at 10 h of infection, IRF-7 (Figure 6A), ISG15 (Figure 6C) and Mx1 (Figure 6D) expression were significantly down-regulated (p<0.05) while STING expression (Figure 6B) was significantly up-regulated (p<0.05); expression of IFN-β and IL-6 was unchanged (Figure 6 E–F). The gene discussed is ISG15; the disease is infection.