TP53 and osteosarcoma: The NARF6 cells which were originally derived from human osteosarcoma U2OS (ATCC) cells, express wt-p53 as well as support the IPTG (isopropyl β-D-1-thiogalactopyranoside) -regulated expression of the p14ARF (Alternate Reading Frame), an upstream regulator of p53 during oncogenic stimulation [41].