Moreover, lenalidomide significantly increased the rituximab-mediated cytotoxic activity of NK cells (1.5-fold) and NKT-like cells (1.6-fold) against leukemia cells (Figures 7(a) and 7(b)), but no effect was observed on CD8 T cells (shown in Figure 7(a)). The gene discussed is CD8A; the disease is leukemia.