FASN is expressed at relatively low levels in normal cells (except liver, brain, lung and adipose tissue), whereas it is highly expressed in a wide variety of cancers, including cancer of the prostate, breast, brain, lung, ovary, endometrium, colon, thyroid, bladder, kidney, liver, pancreas, stomach, oesophagus, eye, mesothelium and skin (reviewed in [3]). The gene discussed is FASN; the disease is Familial prostate cancer.