APOA5 and chronic kidney disease: There exist a considerable number of reports supporting these effects of APOA5 SNPs on blood triglyceride levels [10, 12, 13], and given the potentially important roles of blood triglyceride concentrations in the development of human CKD [13, 14], the modulation of blood triglyceride levels due to these APOA5 SNPs may contribute to the genesis of CKD in humans.