NSCLC cell line H1792 was selected for two reasons: 1) H1792 cells express a low level of endogenous GPRC5A (Figure 3A), thus expression of exogenous GPRC5A-WT and GPRC5A-4 F could be detected and evaluated; and 2) this cell line expresses endogenous EGFR (Figure 3A), thus EGFR activity can be induced by EGF. This evidence concerns the gene EGFR and non-small cell lung carcinoma.