GPT and urticaria: In the toxicological and clinic research, the most common adverse effects of piperaquine are dizziness, headache and gastrointestinal symptoms (nausea, vomiting, diarrhoea and abdominal pain) with less frequent side effects including urticaria, elevated serum alanine aminotransferase (ALT), low serum glucose, prolonged electrocardiographic QT interval and decreased white cell count[9–11].