TTR and hypothyroidism: Patients with incident hypothyroidism were characterized by elevated relative amounts of unmodified TTR [32.8% (22.3–51.2) versus 26.2% (14.0–44.0); P = 0.001] and reduced relative amounts of Gly-TTR [3.34% (1.13–6.63) versus 3.89% (1.62–8.20), P = 0.038], sulphTTR [3.61% (1.98–5.61) versus 8.70% (2.03–12.5), P = 0.001], cysglyTTR [8.82% (3.05–13.3) versus 14.1% (5.22–19.3), P < 0.001] and glutTTR [1.05% (0.00–2.16) versus 4.32 (0.65–7.61), P < 0.001].