Moreover, the PCOS patients also had significantly elevated levels of glucose, insulin at 2 hour during the oral glucose tolerance test, and HbA1C (glucose: 110.4 ± 36.2 mg/dL; insulin: 54.8 ± 52.0 mg/dL; HbA1C: 5.5 ± 0.5 (%) ) compared with the control subjects (glucose: 99.0 ± 25.9 mg/dL; insulin: 32.5 ± 26.5 mg/dL; HbA1C: 5.3 ± 0.3 (%)). This evidence concerns the gene INS and polycystic ovary syndrome.