These glycosides, namely isorhamnetin 3-O-β-d-glucoside and quercetin 3-O-β-d-glucoside are suggested to be possible bioactive reagents of S. herbacea, responsible for relieving the effect of osteoporosis through regulation of adipogenesis/osteoblastogenesis imbalance by inhibiting PPARγ pathway and enhancing bone formation. Here, PPARG is linked to osteoporosis.