By comparison, when the cut-off level for [mut]/([wt]+[mut]) values was set at 1.5×10−2, according to ROC curve (Supplemental Figure 1), 38 cases were judged positive for the G17V RHOA mutation, including 29 AITL and 9 PTCL-NOS. Here, RHOA is linked to mature T-cell and NK-cell non-Hodgkin lymphoma.