Hyperglycemia persisted in the diabetic animals and was 31.2 ± 1.7 mmol·L−1 after 6 weeks of diabetes as compared with 4.7 ± 0.7 mmol·L−1 in the nondiabetic control animals but 3-week chronic treatment with Ang-(1-7) (30.8 ± 1.4 mmol·L−1) did not significantly reduce blood glucose levels. This evidence concerns the gene ANG and diabetes mellitus.