Infection in the 5-LO−/− mice resulted in a reduction of cytokine release related to the Th17 axis such as IL-17, TNF-α, IL-23, and IL-6 (Figures 4(b)–4(e)); however, neither IFN-γ (Figure 4(a)), IL-1β (Figure 4(f)), nor TGF-β (Figure 4(g)) productions were affected by a specific stimulus, compared to that obtained in the infected WT mice when stimulated with SLA. This evidence concerns the gene TNF and infection.