In addition, high NSPs diets have also been associated with Necrotic Enteritis (NE), a multi-factorial disease caused by Clostridium perfringens (CP) that is probably the most important bacterial disease in terms of economic implications in broiler chickens (Hofacre, 2001; Annett et al., 2002; Timbermont et al., 2011). This evidence concerns the gene CP and bacterial infectious disease.