Impaired Bdnf expression or signaling through its receptor TrkB was linked to learning and memory problems and to development of anxiety in several transgenic and stress models of brain disorders (Minichiello et al., 1999; Soliman et al., 2010; Karpova et al., 2011; Kemppainen et al., 2012; Lai et al., 2012). Here, BDNF is linked to Anxiety.