DRD1 and Anxiety: In mammals, the dopaminergic innervation of the intercalated amygdalar cells mostly originate from neurons of the ventral tegmental area and act by way of dopamine D1 receptors, thus modulating the projection of these intercalated cells to the central amygdala and their role in fear/anxiety responses and in fear extinction (reviewed by Pérez de la Mora et al., 2010; Palomares-Castillo et al., 2012).