TNFα, IL-17, and IL-21 have also have also been linked to stroke progression (Barone et al., 1997; Li et al., 2001; Pan and Kastin, 2007; Gelderblom et al., 2012; Swardfager et al., 2013; Clarkson et al., 2014). The gene discussed is TNF; the disease is Stroke.