Greater reactivity to MBP was correlated with stroke severity on admission, larger infarctions, and worse outcome at follow-up, whereas increased reactivity to neuronal-derived antigens, such as microtubule-associated protein-2 and NMDA receptor subunit NR-2A, was correlated with smaller infarctions and better long-term outcome (Planas et al., 2012). The gene discussed is MBP; the disease is Stroke.