CD4 and Cryptococcal meningitis: This approach has been shown to decrease the incidence in the development of cryptococcal meningitis in asymptomatic patients who receive pre-emptive treatment with fluconazole (800 mg orally ×2 weeks, followed by 400 mg orally ×8 weeks, followed by 200 mg orally daily until CD4>200) after screening positive with the CrAg LFA.