In addition, the expression of gene coding for interlukin-1 receptor-associated kinase 2 (IRAK2) proteins which activates nuclear factor kappa-B (NF-kB) was up-regulated in glioblastoma cells, KNS60, and down-regulated in medulloblastoma cells, ONS76. The gene discussed is NFKB1; the disease is glioblastoma.