Namely, we examined the expression of miR-188 and its target genes in NPC tissues using qRT-PCR, and an inverse correlation between miR-188 and CCND1, CCNA2, CCND3, CCNE1, CDK2 or CDK4 expression was identified in patient samples (Figure 2E). This evidence concerns the gene CDK2 and nasopharyngeal carcinoma.