In another study involving analysis of bile in patients from pancreatic adenocarcinoma, several proteins were identified [10]; of these, proteins such as serum albumin, ceruloplasmin, alpha-2-macroglobulin, vitamin D-binding protein, apolipoprotein A-I were also found to be abundantly expressed in malignant strictures in our study. This evidence concerns the gene APOA1 and pancreatic adenocarcinoma.