Importantly, three patients, including two with a past history of ITP, had decreased platelet counts of 9.5, 10.3, and 7.1 × 104/μl, and carried GNE mutations of p. R420X/ p. V572L, 383insT/ p. V572L, and p. R8X/p. This evidence concerns the gene GNE and autoimmune thrombocytopenic purpura.