In contrast to increased FGL-2 activity in PBMC from lymphoma patients no significant difference in FGL-2 mRNA was observed in the PBMC of normal controls (n = 13), patients with active B-cell lymphoma (n = 12) or lymphoma patients in remission (n = 7) (Figure 2A). The gene discussed is FGL2; the disease is B-cell non-Hodgkin lymphoma.