A 4th rat (not shown) did not initially develop classical EAE via the first immunization, but after the subsequent booster of rat IgV-MOG in IFA, exhibited monophasic atypical disease from day 42 to 49 characterized by forelimb weakness, ataxia without tail paralysis, and rigid asymmetrical limb extension (maximal score = 1.0). Here, MOG is linked to Ataxia.