PTPRO and colorectal neoplasm: Furthermore, data-mining of proteomics data from 461 primary colorectal tumor revealed that increased phosphorylation of SRC at Y416 (p=0.039) is observed in tumors with low PTPRO expression (cBioPortal, Cerami et al., 2012, http://cbioportal.org/public-portal/) (Figure 2E).