To study the effects of PLX4032 and PLX4720 on ABCG2, an ABCG2-expressing sub-line of the BRAF wild-type neuroblastoma cell line UKF-NB-3 (UKF-NB-3ABCG2) was used that had been established by lentiviral transduction with LeGO vectors (http://www.lentigo-vectors.de) as described previously [21, 22]. Here, ABCG2 is linked to neuroblastoma.