Escape from apoptosis is an almost systematic hallmark of cancer cells that contributes to tumor progression and drug resistance.3 The BCL-2 family members constitute essential intracellular players in the apoptotic machinery.4 This family is composed of pro- and anti-apoptotic proteins sharing at least one of four BCL-2 homology domains (BH1 to 4). This evidence concerns the gene BCL2 and cancer.