ADGRE1 and Other metabolic disease: We quantified by qPCR mRNAs for macrophage markers (Itgax = integrin alpha X = CD11c and Emr1 = EGF-like module containing, mucin–like, hormone receptor-like sequence = F4/80) and inflammatory chemokines (Ccl3 = chemokine C-C motif ligand 3 = Mip1α and Ccl2 =  chemokine C-C motif ligand 2 = MCP1) in respect to other well known mouse models of metabolic disease (Lepob and Leprdb).