Genes that were listed in OMIM (http://www.ncbi.nlm.nih.gov/omim) as causing or increasing susceptibility to ALS were included in this list, as well as two genes that have very recently been tied to sporadic ALS and frontotemporal lobar degeneration (FTLD), EWSR1 and TAF15[7], [8], [34]. This evidence concerns the gene EWSR1 and amyotrophic lateral sclerosis.