For example, mutations in hnRNPA1 and hnRNPA2/B1 were found in ALS families and in multisystem proteinopathy [9], TIA1 mutations were identified in Welander distal myopathy [10], [11] and also associated with stress granule formation in ALS [12]. This evidence concerns the gene HNRNPA1 and amyotrophic lateral sclerosis.