At the 5q31, we highlight IL4-590/IL4-RP2* T183 frequency, which is significantly lower in the reference set (8.8%) than overall asthma (16.8%, p-value = 0.019), persistent asthma (18.2%, p-value = 0.011), and moderate-severe asthma (26.7%, p-value = 3×10-4). Here, IL4 is linked to asthma.