The results described above are corroborated by the allelic counts (Additional file 2) of IL4-590*T, which are significantly higher in asthma patients (19.4%; χ2 p-value = 0.010, OR 2.060, 95% CI 1.178-3.601), in persistent asthma (20.3% χ2 p-value = 0.009, OR 2.178 95% CI 1.208-3.925), and in moderate-severe (28.3%, χ2 p-value = 4.514*10-4, OR 3.386 95% CI 1.668-6.877) vs. the reference set (10.5%). This evidence concerns the gene IL4 and asthma.