Genotypes IL4-RP2*183253/183183 were significantly more frequent in asthma patients (30.7% vs. 18.2%; χ2 p-value = 0.027; OR 1.984, 95% CI 1.040-3.788), in persistent asthma (33.8% vs. 18.2%; χ2 p-value = 0.013; OR 2.296, 95% CI 1.159-4.547), and in the moderate-severe asthma vs. the reference set (46.7% vs. 18.2%; χ2 p-value = 0.002; OR 3.938, 95% CI 1.657-9.357). The gene discussed is IL4; the disease is asthma.