ADAM33 and asthma: The TDT analysis in Table 7 suggests that the ADAM33-V4*C allele is significantly over transmitted to offsprings in overall asthma (ratio 27/15 of transmitted/non-transmitted; McNemar χ2 3.429, p-value = 0.044, OR 1.800, 95% CI 0.956-3.384), in persistent asthma (ratio 22/9 of transmitted/non-transmitted; McNemar χ2 5.452, p-value = 0.015 OR 2.444, 95% CI 1.126-5.309), and in mild asthma (ratio 16/4 of transmitted/non-transmitted; McNemar χ2 7.200 p-value = 0.006 OR 4.000, 95% CI 1.337-11.965).