ADRB2-c.16*AG was significantly more frequent in moderate-severe asthma vs. mild asthma (66.7% vs. 36.4%, p-value = 0.010, OR 3.500, 95% CI 1.318-9.293) while GSDML-236*TT displays a significant opposite trend (20.0% and 50.0%, respectively in moderate-severe and mild asthma; χ2 p-value = 0.008, 0R 0.250 95% CI 0.086-0.730). Here, ADRB2 is linked to asthma.