NLRP3 and hepatocellular carcinoma: Luteoloside, isolated from the medicinal plant Gentiana macrophylla, has been demonstrated to show an anticancer effect against hepatocellular carcinoma (HCC) cells through its effect of inhibiting the NLRP3 inflammasome through inhibiting proliferation, invasion, and metastasis of HCC cells in a mouse lung metastasis model [61].