However, Zhimin Li et al. reported that MiR-27a may up-regualte MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells [19], Li H et al. also reported that miR-106a may be involved in the development of drug resistance and the regulation of PDCD4 expression [20]. Here, ABCB1 is linked to ovarian carcinoma.