It is also noteworthy that, compared to ASCs-CM, hUCESCs-CM contain lower levels of factors known to participate in cancer progression, such as EGFR [43], FGF 4 and 9 [44-45], ICAM3 [46], IL6 [47], IL6R [48], MCP3 (CCL7) [49], MIF [50], sgp130[48] and VEGFD[51]. Here, IL6 is linked to cancer.