Of note, RP3-443C4.2 was positively correlated with the expression of 24 neighboring and distant genes, including ESR1, GATA3, and ZNF703. ZNF703 is an oncogene commonly associated with luminal B breast cancer, and was previously shown to have differential control of luminal and basal progenitors in epithelial cells of the breast [30]. Here, ESR1 is linked to breast cancer.