Subsequent multivariate analysis confirmed that lower prothrombin time INR (OR 0.01, 95% CI 0.01–0.32), greater total cholesterol (OR 1.04, 95% CI 1.01–1.06), cirrhosis (OR 4.07, 95% CI 1.22–13.59), and ≥ 3 rounds IHIO (OR 7.34, 95% CI 1.90–28.39) were the independent risk factors for hyperglycemia (Table 2). The gene discussed is F2; the disease is Hyperglycemia.