In a more recent analysis, we identified and characterized a myeloid subpopulation from hemangiosarcoma cell lines that showed the expression of markers associated with bone marrow-derived myeloid progenitors (CD14 and CD115 or the colony stimulating factor 1 receptor, CSF-1R) co-expressed with surface markers associated with endothelial progenitor (CD34 and CD133) and endothelial cell differentiation (CD105, CD146, and αvβ3)[8]. The gene discussed is PROM1; the disease is angiosarcoma.