The results of the present study demonstrate a marked positive correlation between the expression levels of BIRC5, CCNE1 and EGFR. Furthermore, a dependence was observed between the levels of BIRC5 mRNA and those of the MKI67 marker of proliferation, which may indicate that cell survival and proliferation are closely associated in bladder cancer. The gene discussed is CCNE1; the disease is urinary bladder carcinoma.