However, a significant positive correlation between the overexpression of EZH2, focal adhesion kinase (FAK) and phosphorylated FAK, as wells as angiolymphatic invasion and lymph node metastasis in endometrial cancer were identified by Zhou et al (25), suggesting that EZH2 may regulate endometrial cancer migration along with FAK through modulating E-cadherin. The gene discussed is PTK2; the disease is endometrial cancer.