CDH1 and endometrial cancer: However, a significant positive correlation between the overexpression of EZH2, focal adhesion kinase (FAK) and phosphorylated FAK, as wells as angiolymphatic invasion and lymph node metastasis in endometrial cancer were identified by Zhou et al (25), suggesting that EZH2 may regulate endometrial cancer migration along with FAK through modulating E-cadherin.