By silencing EZH2, the mRNA expression levels of E-cadherin and Keratin 18 increased by 177 and 158%, respectively; while mesenchymal markers, β-catenin and N-cadherin, decreased by 18.04 and 41.18%, respectively, in nasopharyngeal carcinoma cells (20). This evidence concerns the gene KRT18 and nasopharyngeal carcinoma.