Furthermore, overexpression of the Survivin gene in gastric cancer cells has been associated with the resistance to docetaxel-based chemotherapy in patients with advanced gastric cancer (15), and the overexpression of the Survivin gene induced by CDDP has been demonstrated to aid cancer cells in overcoming the apoptosis checkpoint at the G2/M phase of the cell cycle (16). Here, BIRC5 is linked to cancer.