MYH14 and heart disorder: Presented in this article study focuses on one particular sarcomeric protein, the essential light chain of myosin that is located in the neck region of the myosin cross-bridge (Rayment et al., 1993), and was shown to be important for myosin contractile function in health and in heart disease (Sawicki et al., 2005; Kazmierczak et al., 2009, 2013; Muthu et al., 2011; Cadete et al., 2012).