Between the ubiquitin-proteasome system, two E3 ubiquitin ligases, muscle RING-finger protein-1 (MuRF1) and muscle atrophy F-box (MAFbx/atrogin-1), play an important role in muscle atrophy; they are called atrogenes and serve as early markers of skeletal muscle atrophy, aiding in the diagnosis of muscle disease [5]. This evidence concerns the gene FBXO32 and muscular atrophy.