BDKRB2 and infection: Extending this analysis to in vitro infection models, we showed that antagonists of B2R (HOE-140) or B1R (DAL8-BK) efficiently reversed the upregulated phagocytic uptake of L. major Δisp2/3 by TG-macrophages without interfering with the internalization of ISP-expressing (WT) promastigotes.