Indeed, miR-19a-3p and miR-19b-3p, members of the oncogenic miR-17-92 cluster, have been shown to be direct transcriptional targets of MYCN in neuroblastoma cells [5,24], and the region upstream to miR-494-3p contains E-box sequences (data not shown), suggesting that MYCN can induce its expression. Here, MYCN is linked to neuroblastoma.