It has previously been reported that deletion of the GluN1 subunit in the CA1 region of the hippocampus results in reduced expression of the GluN2B subunit in the dendrites of pyramidal neurons in mice [23], suggesting our finding of reduced GluN2B in the hippocampus could be associated with the reductions in GluN1 previously reported in the left hippocampus in schizophrenia. This evidence concerns the gene GRIN1 and schizophrenia.