Some replicated findings include a decrease in GluN1 mRNA in the dentate gyrus of schizophrenia patients [7,8], a decrease or no change in NMDAR binding density [7,9,10] and most interestingly a more pronounced decrease in NMDAR binding and GluN1 mRNA and protein in the left hippocampus of schizophrenia subjects compared to the right [8,9,11]. Here, GRIN1 is linked to schizophrenia.