TGM2 and rickets: It also showed dense transverse lines in tibia and ulna suggestive of looser’s zones indicative of severe rickets (Figures 2 and 3).Anti- endomysial antibodies titer was 80 (normal is negative), anti-tissue transglutaminase IgA was positive 75 U/ml (normal <2.5 U/ml) and anti-tissue transglutaminase IgG was negative.